Department of the Structure and Function of Chromosomes

Laboratory of Molecular Genetics

Vershinin Alexander
Head of the Laboratory

Staff: 
      Name Position Academic
degree
Contacts
thomson_logo.gif scopus_logo.jpg Vershinin Alexander head DSc (Biology) avershinatmcb [dot] nsc [dot] ru
thomson_logo.gif     Evtushenko Elena senior research fellow PhD (Biology) evtatmcb [dot] nsc [dot] ru
thomson_logo.gif     Terletsky Alexander research fellow PhD (Biology)  
thomson_logo.gif scopus_logo.jpg   Veryaskina Yulia research fellow PhD (Biology)  
thomson_logo.gif     Lipikhina Yulia research assistant   lipikhinaatmcb [dot] nsc [dot] ru
thomson_logo.gif     Gatskaya Sima research assistant    
      Trunin Sergey research assistant    
      Serdyukova Olga lab technician    
      Titov Sergey part-time senior research fellow PhD (Biology)  
      Ivanov Mikhail part-time research fellow PhD (Biology)  
      Elisaphenko Evgeny part-time research fellow PhD (Biology)  
      Malakhina Ekaterina part-time research assistant PhD (Biology)  
      Klimova Olesya part-time research assistant    
      Maslov Konstantin part-time research assistant    

Former research workers

Gaskov Dmitry
Kolesnikov Nikolay, DSc

Recent publications: 
  1. Kolesnikov NN, Veryaskina YuA, Titov SE, Rodionov VV, Gening TP, Abakumova TV, Kometova VV, Torosyan MKh, Zhimulev IF. Expression of micrornas in molecular genetic breast cancer subtypes. Cancer Treatment and Research Communications, 2016, doi: 10.1016/j.ctarc.2016.08.006

  2. Stolyar M, Klimova O, Ivanov M, Gorbenko A, Titov S, Olkhovskiy I. JAK2 haplotype 46/1 (GGCC) has no effect on the primary risk of JAK2 V617F mutation, but it strongly potentiates the progression of grown allele burden in myeloproliferative neoplasms. Haematologica 102(s2): 539, 2017

  3. Malek A, Sleptsov I, Cheburkin Y, Samsonov R, Kolesnikov N. miRNA as potential tool for thyroid cancer diagnostics and follow up: practical considerations. JSM Thyroid Disord Manag 2(1): 1007, 2017
  4. Boldyreva LV, Goncharov FP, Demakova OV, Zykova TYu, Levitsky VG, Kolesnikov NN, Pindyurin AV, Semeshin VF, Zhimulev IF. Protein and genetic composition of four chromatin types in Drosophila melanogaster cell lines. Curr Genomics, 18(2): 214-226, 2017

  5. Stupak EV, Veryaskina YuA, Titov SE, Achmerova LG, Stupak VV, Ivanov MK, Zhimulev IF, Kolesnikov NN. MicroRNA profiling in the malignant progression of gliomas. AIP Conf Proc 1760, 020065, doi: 10.1063/1.4960284, 2016

  6. Evtushenko  EV, Levitsky VG, Elisafenko EA, Gunbin KV, Belousov AI, Šafář J, Doležel J, Vershinin AV. The molecular mechanisms of heterochromatin expansion in rye chromosomes. Cytogenet Genome Res 148: 91, 2016

  7. Titov SE, Demenkov PS, Ivanov MK, Malakhina ES, Poloz TL, Tsivlikova EV, Ganzha MS, Shevchenko SP, Gulyaeva LF, Kolesnikov NN. Selection and validation of miRNAs as normalizers for profiling expression of microRNAs isolated from thyroid fine needle aspiration smears. Oncology Rep 36: 2501-2510, 2016

  8. Samsonov R, Burdakov V, Shtam T, Radzhabovа Z, Vasilyev D, Tsyrlina E, Titov S, Ivanov M, Berstein L, Filatov M, Kolesnikov N, Gil-Henn H, Malek A. Plasma exosomal miR-21 and miR-181a differentiates follicular from papillary thyroid cancer. Tumor Biol 37: 12011-12021, 2016

  9. Evtushenko EV, Levitsky VG, Elisafenko EA, Gunbin KV, Belousov AI, Šafář J, Doležel J, Vershinin AV. The expansion of heterochromatin blocks in rye reflects the co-amplification of tandem repeats and adjacent transposable elements. BMC Genomics 17(1): 337, 2016

  10. Titov SE, Ivanov MK, Karpinskaya EV, Tsivlikova EV, Shevchenko SP, Veryaskina YA, Akhmerova LG, Poloz TL, Klimova OA, Gulyaeva LF, Zhimulev IF, Kolesnikov NN. miRNA profiling, detection of BRAF V600E mutation and RET-PTC1 translocation in patients from Novosibirsk oblast (Russia) with different types of thyroid tumors. BMC Cancer 16: 201, 2016

  11. Shevchenko S, Mostovich L, Kolesnikov N, Gulyaeva L. Molecular biomarkers in preoperative diagnosis of thyroid cancer. Eur J Cancer Suppl 13(1): 52, 2015

  12. Vershinin AV, Evtushenko EV. What is the specificity of plant subtelomeres? In: "Subtelomeres" (Louis EJ, Becker MM, Eds), Springer-Verlag Berlin Heidelberg, pp 195-210, 2014

  13. Levitsky VG, Babenko VN, Vershinin AV. The roles of the monomer length and nucleotide context of plant tandem repeats in nucleosome positioning. J Biomol Struct Dyn 32: 115-126, 2014

  14. Chanyshev MD, Kosorotikov NI, Titov SE, Kolesnikov NN, Gulyaeva LF. Expression of microRNAs, CYP1A1 and CYP2B1 in the livers and ovaries of female rats treated with DDT and PAHs. Life Sci 103: 95-100, 2014

  15. Gulyaeva LF, Chanyshev MD, Kosorotikov NI, Kolesnikov NN. miRNA in post-transcriptional regulation of tissue-specific cytochrom P450 activity in female Wistar rats. Protein Sci 22(S1): 225, 2013

Selected talks: 
  1. Vershinin A. The molecular mechanisms of the heterochromatin expansion in the rye chromosomes. 21st International Chromosome Conference. July 10-13, 2016, Foz do Iguaçu, Brazil

  2. Vershinin AV. Intensive recombinations have led to tandem repeat expansion and enlargement of rye subtelomeric heterochromatin. The 19th International Chromosome Conference. 2-6 September 2013, Bologna, Italy

  3. Vershinin AV. Genomics of rye subtelomeric heterochromatin. 11th Gatersleben Research Conference "Chromosome biology, genome evolution, and speciation" 23-25 April 2012, Gatersleben, Germany

  4. Vershinin AV. The genomics of the most abundant tandem repeat DNA families in the rye heterochromatin. Annual Main Meeting of the Society for Experimental Biology. Chromosome Organization and Cytogenomics, 30 June - 3 July 2010, Prague, Czech Republic

  5. Kolesnikov NN. X-chromosome inactivation, mobile elements and ncRNA genes. 6th International Conference on Bioinformatics of Genome Regulation and Structure, 22-28 June 2008, Novosibirsk, Russia

  6. Kolesnikov NN. Evolution of the structure of the XIST locus in mammals. 5th International Conference on Bioinformatics of Genome Regulation and Structure, 16-22 July 2006, Novosibirsk, Russia