Department of Regulation of Genetic Processes

Laboratory of Genomics

Belyakin Stepan
Head of the Department
Head of the Laboratory

Staff: 
thomson_logo.gif scopus_logo.jpg Belyakin Stepan head PhD (Biology) belyakinatmcb [dot] nsc [dot] ru
thomson_logo.gif scopus_logo.jpg Shloma Victor senior research fellow PhD (Biology) shlomaatmcb [dot] nsc [dot] ru
thomson_logo.gif scopus_logo.jpg Posukh Olga research fellow PhD (Biology)  
thomson_logo.gif scopus_logo.jpg Laktionov Petr research fellow PhD (Biology) laktionovatmcb [dot] nsc [dot] ru
thomson_logo.gif scopus_logo.jpg Maksimov Daniil research fellow PhD (Biology) viftatmcb [dot] nsc [dot] ru
thomson_logo.gif scopus_logo.jpg Yurlova Anna junior research fellow PhD (Biology) annushatmcb [dot] nsc [dot] ru
thomson_logo.gif scopus_logo.jpg   Kalashnikova Darya research assistant   tsunatmcb [dot] nsc [dot] ru
thomson_logo.gif scopus_logo.jpg   Antoshina Polina research assistant   poloniumatmcb [dot] nsc [dot] ru
thomson_logo.gif scopus_logo.jpg   Romanov Stanislav part-time research assistant   romanovatmcb [dot] nsc [dot] ru

Former research workers:

Sinitsyn Ivan
Skvortsova Ksenia

Recent publications: 
  1. Belyakin SN, Maksimov DA, Pobedintseva MA, Laktionov PP, Voronova D. ASIP promoter variants predict the sesame coat color in Shiba Inu dogs. (doi: 10.3390/vetsci9050222Vet Sci 9(5): 222, 2022

  2. Ilyin AA, Kononkova AD, Golova AV, Shloma VV, Olenkina OM, Nenasheva VV, Abramov YuA, Kotov AA, Maksimov DA, Laktionov PP, Pindyurin AV, Galitsyna AA, Ulianov SV, Khrameeva EE, Gelfand MS, Belyakin SN, Razin SV, Shevelyov YuY. Comparison of genome architecture at two stages of male germline cell differentiation in Drosophila. (doi: 10.1093/nar/gkac109Nucleic Acids Res  50(6): 3203–3225, 2022

  3. Bryzgunova O, Bondar A, Ruzankin P, Laktionov Petr, Tarasenko A, Kurilshikov A, Epifanov R, Zaripov M, Kabilov M, Laktionov Pavel. Locus-specific methylation of GSTP1, RNF219, and KIAA1539 genes with single molecule resolution in cell-free DNA from healthy donors and prostate tumor patients: application in diagnostics. (doi: 10.3390/cancers13246234Cancers 13(24): 6234, 2021

  4. Romanov SE, Kalashnikova DA, Laktionov PP. Methods of massive parallel reporter assays for investigation of enhancers. (doi: 10.18699/VJ21.038) Vavilov J Genet Breed 25(3): 344-355, 2021

  5. Kalashnikova DA, Maksimov DA, Romanov SE, Laktionov PP, Koryakov DE. SetDB1 and Su(var)3-9 play non-overlapping roles in somatic cell chromosomes of Drosophila melanogaster. (doi: 10.1242/jcs.253096) J Cell Sci 134(2): jcs253096, 2021

  6. Gilbert M, ..., Belyakin S, Yurlova AA, ..., Cleaveland S. Distemper, extinction, and vaccination of the Amur tiger. (doi: 10.1073/pnas.2000153117Proc Natl Acad Sci USA 117(50): 31954-31962, 2020

  7. Singh PB, Belyakin SN, Laktionov PP. Biology and physics of heterochromatin-like domains/complexes. (doi: 10.3390/cells9081881Cells 9(8): 1881, 2020

  8. Chernonosova VS, Laktionov Petr P, Murashov IS, Karpenko AA, Laktionov Pavel P. Comparative gene expression profiling of human primary endotheliocytes cultivated on polyurethane-based electrospun 3D matrices and natural decellularized vein. (doi: 10.1088/1748-605X/ab7d84Biomed Mater 15(4): 045012, 2020

  9. Stepanova AO, Laktionov Petr P, Cherepanova AV, Chernonosova VS, Shevelev GY, Zaporozhchenko IA, Karaskov AM, Laktionov Pavel P. General study and gene expression profiling of endotheliocytes cultivated on electrospun materials. (doi: 10.3390/ma12244082Materials 12(24): 4082, 2019

  10. Maksimov DA, Koryakov DE. Binding of SU(VAR)3-9 partially depends on SETDB1 in the chromosomes of Drosophila melanogaster. (doi: 10.3390/cells8091030Cells 8(9): 1030, 2019

  11. Novikova OA, Nazarkina ZK, Cherepanova AV, Laktionov Petr P, Chelobanov BP, Murashov IS, Deev RV, Pokushalov EA, Karpenko AA, Laktionov Pavel P. Isolation, culturing and gene expression profiling of inner mass cells from stable and vulnerable carotid atherosclerotic plaques. (doi: 10.1371/journal.pone.0218892PLoS ONE 14(6): e0218892, 2019

  12. Singh PB, Shloma VV, Belyakin SN. Maternal regulation of chromosomal imprinting in animals. (doi: 10.1007/s00412-018-00690-5) Chromosoma 128(2): 69-80, 2019

  13. Singh PB, Belyakin SN. L chromosome behaviour and chromosomal imprinting in Sciara coprophila. (doi: 10.3390/genes9090440Genes 9(9): 440, 2018

  14. Laktionov PP, Maksimov DA, Romanov SE, Antoshina PA, Posukh OV, White‑Cooper H, Koryakov DE, Belyakin SN. Genome‑wide analysis of gene regulation mechanisms during Drosophila spermatogenesis. (doi: 10.1186/s13072-018-0183-3Epigenetics Chromatin 11: 14, 2018

  15. Maksimov DA, Laktionov PP, Posukh OV, Belyakin SN, Koryakov DE. Genome-wide analysis of SU(VAR)3-9 distribution in chromosomes of Drosophila melanogaster.  (doi: 10.1007/s00412-017-0647-4Chromosoma 127(1): 85-102, 2018

  16. Gayner TA, Karamysheva TV, Karimova OG, Koren OL, Shloma VV, Shorina AR, Bogomolov AG, Rubtsov NB. Comprehensive chromosomal pathology diagnostic of derivative of the 4 chromosome and the small supernumerary marker chromosome. Med Genetics 16(12): 9-17, 2017 (paper in Russian with abstracts in English)

  17. Posukh OV, Maksimov DA, Laktionov PP, Koryakov DE, Belyakin SN. Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile. (doi: 10.1186/s13072-017-0163-zEpigenetics Chromatin 10: 56, 2017

  18. Ilyin AA, Ryazansky SS, Doronin SA, Olenkina OM, Mikhaleva EA, Yakushev EY, Abramov YA, Belyakin SN, Ivankin AV, Pindyurin AV, Gvozdev VA, Klenov MS, Shevelyov YY. Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells. (doi: 10.1093/nar/gkx355Nucleic Acids Res 45(13): 7666-7680, 2017

  19. Andreyeva EN, Bernardo TJ, Kolesnikova TD, Lu X, Yarinich LA, Bartholdy BA, Guo X, Posukh OV, Healton S, Willcockson MA, Pindyurin AV, Zhimulev IF, Skoultchi AI, Fyodorov DV. Regulatory functions and chromatin loading dynamics of linker histone H1 during endoreplication in Drosophila. (doi: 10.1101/gad.295717.116Genes Dev 31: 603-616, 2017

  20. Ogneva IV, Belyakin SN, Sarantseva SV. The development of Drosophila melanogaster under different duration space flight and subsequent adaptation to Earth gravity. (doi: 10.1371/journal.pone.0166885PLoS ONE 11(11): e0166885, 2016

  21. Maksimov DA, Laktionov PP, Belyakin SN. Data analysis algorithm for DamID-seq profiling of chromatin proteins in Drosophila melanogaster. (doi: 10.1007/s10577-016-9538-4Chromosome Res 24: 481-494, 2016

  22. Munzarova A, Popova J, Razuvaeva A, Shloma V, Gatti M, Omelyanchuk L. Accurate measurement of poleward microtubule flux in the spindle of Drosophila S2 cells. (doi: 10.1002/cbin.10638) Cell Biol Int 40: 984-990, 2016

  23. Posukh OV, Maksimov DA, Skvortsova KN, Koryakov DE, Belyakin SN. The effects of SUUR protein suggest its role in repressive chromatin renewal during replication in Drosophila. (doi: 10.1080/19491034.2015.1074366) Nucleus 6: 249-253, 2015

  24. Pokholkova GV, Koryakov DE, Pindyurin AV, Kozhevnikova EN, Belyakin SN, Andreyenkov OV, Belyaeva ES, Zhimulev IF. Tethering of SUUR and HP1 proteins results in delayed replication of euchromatic regions in Drosophila melanogaster polytene chromosomes. (doi: 10.1007/s00412-014-0491-8Chromosoma 124: 209-220, 2015

Selected talks: 
  1. Belyakin SN. Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile. International Conference “Chromosome – 2018”, 20-24 August 2018, Novosibirsk, Russia

  2. Laktionov PP. Genome-wide analysis of gene regulation mechanisms during Drosophila spermatogenesis. International Conference “Chromosome – 2018”, 20-24 August 2018, Novosibirsk, Russia

  3. Belyakin S. Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile. International mini-conference “Chromosomes and mitosis – 2017”, December 8, 2017, Novosibirsk

  4. Laktionov PP. Genome-wide profiling of gene expression and transcription factors binding reveals new insights into the mechanisms of gene regulation during Drosophila spermatogenesis. International mini-conference "Chromosomes and Mitosis – 2016", November 25, 2016, Novosibirsk, Russia

  5. Laktionov PP. Transcription factors Cookie monster and Cannonball in regulation of gene expression during Drosophila melanogaster spermatogenesis. Drosophila Genetics and Genomics Course, 27 July – 4 August 2014, Cambridge, UK

  6. Belyakin SN. Putative mechanism of the SUUR protein action in late replicating regions of Drosophila genome. 11th International Conference on Drosophila Heterochromatin, 23-29 June, 2013, Lecce, Italy

  7. Laktionov PP. Identification of transcriptional regulators for testis-specific gene clusters in Drosophila melanogaster. 16th European Workshop on Molecular and Cellular Endocrinology of the Testis, 8-12 May, 2010, La Biodola, Island of Elba, Italy

  8. Belyakin SN. Gene density profile reveals the landmarks of late replicated domains in Drosophila melanogaster genome. 9th International Conference on Drosophila Heterochromatin, 23-30 May 2009, Gubbio, Italy

Collaboration: 
  • The European Molecular Biology Laboratory, Heidelberg, Germany (2002 - 2005)

  • Netherlands Cancer Institute, Amsterdam, Netherlands (2010)

  • University of Toronto, Canada (2011 - 2013)

  • Cardiff University, UK (2011 - 2108)

  • University of Edinburgh, UK

  • Charité – Universitätsmedizin Berlin, Germany

  • Università degli Studi della Tuscia, Viterbo, Italy